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These limitations have motivated researchers to investigate alternative delivery methods that can bypass the BBB while ensuring sufficient patient compliance, preferably avoiding invasive routes like injections

Evidence from in vitro, animal, and small human studies indicates low toxicity

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Inflammation Research , 53 , pp.S31-S32

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A comunidade cientfica ressalta a necessidade de conduzir estudos clnicos controlados para validar as observaes pr-clnicas promissoras